Current use of botulinum neurotoxin in esthetic practice-Clinical guide and review

J Cosmet Dermatol. 2021 Jun;20(6):1648-1654. doi: 10.1111/jocd.14152. Epub 2021 May 3.

Abstract

Background: Botulinum neurotoxin is one of the most versatile and widely used medical products in the world.

Aims: The review's focus is the plastic and dermatologic uses of botulinum neurotoxin currently supported by published data.

Methods: Relevant clinical articles regarding botulinum neurotoxin use in plastic surgery, dermatology, and general esthetic literature were searched and reviewed.

Results: The search yielded 258 studies. Two hundred articles were excluded following title and abstract review. Twenty-one studies were excluded following full-text screening. A total of 37 studies remained and were discussed in this review.

Conclusions: Botulinum neurotoxin is widely used for numerous off-label indications from head to toe. Some uses are well documented, and their safety has been demonstrated in controlled trials, yet most remain poorly researched.

Keywords: Botox; Dysport; aging; botulinum neurotoxin; injectables.

Publication types

  • Review

MeSH terms

  • Botulinum Toxins, Type A*
  • Esthetics
  • Humans
  • Neuromuscular Agents* / therapeutic use
  • Surgery, Plastic*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A